Clinical trials

Statistics report about clinical research

Clinical trials

This report presents key facts and figures about clinical trials worldwide, with a focus on the United States. Clinical trials are also known as Phase I to IV within the research, development, and approval process for new drugs, medical devices, or procedures. This report gives you an overview about health R&D in general, number of clinical studies, success rates, costs, and many more.

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Table of contents

R&D overview

6
  • Premium Statistic Total global pharmaceutical R&D spending 2014-2030
  • Premium Statistic Industry sectors - expenditure on research and development 2022
  • Premium Statistic Top pharmaceutical R&D projects based on net present value May 2024
  • Basic Statistic Research and development expenditure: U.S. pharmaceutical industry 1995-2023
  • Premium Statistic Research and development in European pharmaceutical industry by country 2022
  • Premium Statistic Total clinical research funding by National Institutes for Health 2013-2025

Top R&D companies

5
  • Basic Statistic Global top pharmaceutical companies based on R&D spending 2026
  • Basic Statistic Top 50 global pharmaceutical and biotech companies by R&D intensity in 2023
  • Basic Statistic Top pharmaceutical companies in R&D spending growth 2023
  • Premium Statistic Leading global contract research organizations based on revenue 2023
  • Basic Statistic Roche: participation of patients in clinical trials 2009-2017

Clinical studies

7
  • Basic Statistic Increase in clinical trials' complexity 2001-2015
  • Premium Statistic Clinical trial success rates by therapeutic area 2020
  • Basic Statistic Number of registered clinical studies by location worldwide 2024
  • Basic Statistic Percent of registered clinical studies worldwide by location 2024
  • Basic Statistic Share of recruiting clinical studies worldwide by location 2024
  • Premium Statistic Total number of registered clinical studies worldwide 2000-2024
  • Basic Statistic Total number of registered clinical studies with posted results worldwide 2008-2024

Participation

4
  • Basic Statistic Top clinical trial participant countries worldwide 2015-19, by share
  • Basic Statistic Clinical trial participants U.S. vs. rest of world by therapy area 2015-2019
  • Basic Statistic Clinical trial participants gender share worldwide 2015-19, by geographic location
  • Basic Statistic Clinical trial participants ethnicity share worldwide 2015-19, by geographic location

Costs and market

6
  • Basic Statistic Pharmaceuticals: cost of drug development in the U.S. since 1975
  • Premium Statistic R&D expenditure of new therapeutic drugs 2009-2018
  • Basic Statistic Estimated clinical trial cost per patient by therapeutic class 2015-2017
  • Basic Statistic Estimated clinical trial cost per drug by therapeutic class 2015-2017
  • Basic Statistic CRO market size worldwide forecast 2032
  • Premium Statistic Global pharma CRO market size 2015-2024, by pre-clinical, clinical and discovery

Approvals, launches, setbacks

6
  • Premium Statistic Pharmaceutical industry - number of new substances 1998-2023
  • Premium Statistic Number of novel drugs approved annually by CDER 2008-2023
  • Basic Statistic Key measurements of U.S. CDER drug approvals in 2023
  • Basic Statistic FDA first premarket approvals for medtech products granted 2005-2022
  • Premium Statistic Projection of top 2024 pharma and biotech launches by revenue 2028
  • Basic Statistic Number of unsuccessful Alzheimer’s drugs in development in the U.S. 1998-2017

COVID-19

4
  • Premium Statistic Top companies by COVID-19 treatment vaccines in development June 2022
  • Basic Statistic Number of COVID-19 drugs in development worldwide by phase June 2022
  • Basic Statistic Number of COVID-19 treatment vaccine trials worldwide by phase June 2022
  • Basic Statistic Number of COVID-19 treatment vaccine trials worldwide by type June 2022
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