Top abused prescription drugs U.S. by revenue 2016 | Statista

This statistic shows the 20 most abused pharmaceutical drugs in the United States in 2016, sorted by revenue. According to the data, methlyphenidate HCl was the most abused pharmaceutical drug with 2016 sales reaching over two billion U.S. dollars.

Top 20 most abused prescription drugs in the U.S. in 2016, by revenue (in million U.S. dollars)

Characteristic	Revenue in million U.S. dollars
Methylphenidate HCl	2,073
OxyContin (oxycondone HCl controled-release)	1,390
Celecoxib	1,246
Buprenorphine and naloxone	1,026
Suboxone (buprenorphine and naloxone)	935
Concerta (methylphenidate HCl)	863
Celebrex (celecoxib capsule)	733
Fentanyl	560
Zolpidem tartrate	491
Celecox (celecoxib)	434.5
Adderall XR (amphetamine/dextroamphetamine)	363.8
Sertraline HCL	349
Hydromorphone HCl	316
Ambien (zolpidem tartrate)	304
Zoloft (sertraline HCl)	304
Methylphenidate ER	288
Duragesic (fentanyl transdermal system)	288
Ritalin/Focalin (methylphenidate HCl)	282
Subsys (fentanyl sublingual spray)	242.3
Morphine suflate	132

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Release date

September 2017

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Region

United States

Survey time period

2016

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