Potential Zika virus birth defects rate U.S. 2016-2017

This statistic presents the prevalence of birth defects among infants and fetuses in the U.S. potentially related to Zika virus infections from January 2016 to June 2017. In that year, it was estimated that brain abnormalities or microcephaly related to the Zika virus affected 1.4 out of every 1,000 live births.

Number of cases of infants and fetuses with birth defects potentially related to Zika virus in the U.S. from January 2016 to June 2017 (per 1,000 live births)

Characteristic	Number of cases per 1,000 live births
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Release date

January 2020

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Region

United States

Survey time period

January 1, 2016 to June 30, 2017

Supplementary notes

22 U.S. jurisdictions included births that occurred in California (selected counties), Florida (selected southern counties), Georgia (selected metropolitan Atlanta counties), Hawaii, Illinois, Indiana, Iowa, Louisiana, Massachusetts, Minnesota, New Jersey, New York (excluding New York City residents), North Carolina (selected regions), Oklahoma, Puerto Rico, Rhode Island, South Carolina, Texas (Public Health Regions 10, 11), the U.S. Virgin Islands, Utah, Vermont, and Virginia.

* Congenital microcephaly (head circumference <3rd percentile for gestational age and sex and documentation of microcephaly or a small head in the medical record), intracranial calcifications, cerebral atrophy, abnormal cortical gyral patterns (e.g., polymicrogyria, lissencephaly, pachygyria, schizencephaly, gray matter heterotopia), corpus callosum abnormalities, cerebellar abnormalities, porencephaly, hydranencephaly, ventriculomegaly/hydrocephaly (excluding “mild” ventriculomegaly without other brain abnormalities), fetal brain disruption sequence (collapsed skull, overlapping sutures, prominent occipital bone, scalp rugae), and other major brain abnormalities.

** § Microphthalmia/anophthalmia, coloboma, cataract, intraocular calcifications, and chorioretinal anomalies (e.g., atrophy and scarring, gross pigmentary changes, excluding retinopathy of prematurity); optic nerve atrophy, pallor, and other optic nerve abnormalities.

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