This statistic shows the leading 10 therapeutic drugs in the United States in 2016, based on per-member-per-year spending. The drug Lantus (insulin glargine) for diabetes had the highest PMPY spending, reaching almost 17 U.S. dollars in that year.
Top 10 traditional therapy drugs in the U.S. by per-member-per-year (PMPY) spending in 2016 (in U.S. dollars)*
Characteristic
Per-member-per year spending in U.S. dollars
Lantus (insulin glargine)
16.55
Humalog (insulin lispro injection)
11.68
Metformin
10.67
Vyvanse (lisdexamfetamine)
10.2
Lialda (mesalamine)
8.88
Januvia (sitagliptin)
8.66
Esomeprazole magnesium
8.56
Methylphenidate extended release
8.33
Dextroamphetamine/amphetamine
8.24
Lyrica (pregabalin)
7.8
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* The statistic includes members with
commercial insurance coverage. Members used Express Scripts for retail
and home delivery pharmacy services; they used Accredo, the Express Scripts
specialty pharmacy, for specialty drug prescriptions.
PMPY metrics are calculated by dividing totals by
the total number of member-months, which is determined by adding the number
of months of eligibility for all members in the sample.
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Express Scripts Inc. (February 13, 2017). Top 10 traditional therapy drugs in the U.S. by per-member-per-year (PMPY) spending in 2016 (in U.S. dollars)* [Graph]. In Statista. Retrieved March 13, 2025, from https://www.statista.com/statistics/657058/top-traditional-therapeutic-drugs-in-the-us-by-pmpy-spend/
Express Scripts Inc. "Top 10 traditional therapy drugs in the U.S. by per-member-per-year (PMPY) spending in 2016 (in U.S. dollars)*." Chart. February 13, 2017. Statista. Accessed March 13, 2025. https://www.statista.com/statistics/657058/top-traditional-therapeutic-drugs-in-the-us-by-pmpy-spend/
Express Scripts Inc. (2017). Top 10 traditional therapy drugs in the U.S. by per-member-per-year (PMPY) spending in 2016 (in U.S. dollars)*. Statista. Statista Inc.. Accessed: March 13, 2025. https://www.statista.com/statistics/657058/top-traditional-therapeutic-drugs-in-the-us-by-pmpy-spend/
Express Scripts Inc. "Top 10 Traditional Therapy Drugs in The U.S. by Per-member-per-year (Pmpy) Spending in 2016 (in U.S. Dollars)*." Statista, Statista Inc., 13 Feb 2017, https://www.statista.com/statistics/657058/top-traditional-therapeutic-drugs-in-the-us-by-pmpy-spend/
Express Scripts Inc, Top 10 traditional therapy drugs in the U.S. by per-member-per-year (PMPY) spending in 2016 (in U.S. dollars)* Statista, https://www.statista.com/statistics/657058/top-traditional-therapeutic-drugs-in-the-us-by-pmpy-spend/ (last visited March 13, 2025)
Top 10 traditional therapy drugs in the U.S. by per-member-per-year (PMPY) spending in 2016 (in U.S. dollars)* [Graph], Express Scripts Inc, February 13, 2017. [Online]. Available: https://www.statista.com/statistics/657058/top-traditional-therapeutic-drugs-in-the-us-by-pmpy-spend/
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